|UCLA Technology Available For Licensing|
1. Direct separation of free amino acids.This new polymer strongly interacts with one enantiomeric form of an amino acid or component in a racemic mixture enabling chiral separations. An efficient way of employing the polymer to separate enantiomers of amino acids is by the use of a column containing a high-surface-area of the polymer. Experimental data has shown a separation factor of alpha = 8.4 for dl-phenylalanine using a 250mm column. Since alpha > 2 is considered to be potentially useful commercially, alpha of 8.4 is remarkable.
2. Usable for both analytical and preparative purposes.
3. Uses aqueous solutions and alcohol; no buffer solutions are needed.
4. Easy scale-up.
5. A large chiral recognition capacity compared to natural biopolymers, such as Human Serum Albumin (HSA) and Bovine Serum Albumin (BSA).
7. Can be used as a chiral sensor.
8. Potential for adaptation for pharmaceutical separations.
|Reference: UCLA Case No. 1998-601||US Patent Number: 6,265,615|
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