| UCLA Technology Available For Licensing |
INNOVATION: UCLA researchers have isolated a unique gene from oral wounds, named wound inducible transcript-3.0 (wit3.0). Wit3.0 is synthesized only when injury is created, and wit3.0 helps fibroblasts to pull the surrounding tissue, which may be one of the biological mechanisms to close the wound. UCLA researchers have shown that wit3.0 increases the rate of wound closure and decreases the area of granulation formation. Additionally, UCLA researchers have shown that in rats, the direct administration of a therapeutically effective amount of wit3.0 ameliorates periodontitis. Most importantly, UCLA researchers propose clinical applications of genetic screening of SNPs of wit3.0 in preventive diagnostics of gum diseases and personalized treatments and prognostics.
POTENTIAL APPLICATIONS
| Reference: UCLA Case No. 2005-500 | PCT Application: US06/008678 |
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