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RESEARCH TOOLS, REAGENTS & DRUG DISCOVERY


ANIMAL MODELS
  • 2012-294 mGFAP-Cre-Recombinase Transgenic Mouse Strains
  • 2011-464 Polyclonal Antibody Recognizing the Human RIN2 Protein
  • 2011-463 Monoclonal Antibody Recognizing the Mouse RIN1 Protein
  • 2011-346 FOX-2 (RBFOX2) TRANSGENIC MICE
  • 2011-344 FOX-1 (RBFOX1) TRANSGENIC MICE
  • 2010-706 VE-cadherin-CreERT2 Transgenic Mouse
  • 2010-705 Floxed Mouse For Progesterone Receptor (PRCE)
  • 2010-675 VE-Cadherin-Cre-recombinase Transgenic Mouse
  • 2010-662 Bone Morphogenetic Protein Receptor type 1B (BMPR1B or Alk6) Knockout Mouse
  • 2010-535 Ptgs2 (Cyclooxygenase-2) Luciferase Knock-in Mouse
  • 2010-534 Ptgs2 (Cyclooxygenase-2) Conditional Knockout Mouse
  • 2010-498 SYNAPTOTAGMIN 4 KNOCKOUT MOUSE
  • 2010-496 MALE MICE LACKING SRY ON THE Y CHROMOSOME WITH A FUNCTION AUTOSOMAL SRY TRANSGENE
  • 2010-477 BAC-HTT-WT: HUNTINGTON'S DISEASE MOUSE MODEL BACHD CONTROL LINE
  • 2010-090 A Mouse Model OF Severe Asthma
  • 2009-772 A MOUSE MODEL OF ALLERGIC DISEASE
  • 2009-718 Transgenic Mouse Model of Parkinson's Disease (PD) Exhibiting Age-dependent Disease Progression
  • 2009-556 A NOVEL RAT MODEL OF BISPHOSPHONATE-RELATED OSTEONECROSIS OF THE JAW (BRONJ)
  • 2009-522 Cre/LoxP Conditional Mouse Model of Huntington's Disease
  • 2009-214 IFNAR Knockout Mouse
  • 2009-186 GPAT4 Knockout Mouse
  • 2008-020 Mouse Model for Conditional Knockout of the PTEN Gene
  • 2007-222 Mouse model for Premature Aging: Zmpste24 Knockout Mice
  • 2006-625 Proton-sensing G Protein-couipled Receptor 4 Knockout
  • 2006-624 Mouse Model Deficient for the Proton Sensing GPCR T cell Death-Associated Gene 8 (TDAG8)
  • 2006-215 B-raf/loxP-flanked Mutant Mouse
  • 2005-492 Novel Mouse Model for Huntington's Disease
  • 2005-129 pVEGF-TSTA-Luciferase Mice
  • 2004-644 Adipose Tissue-specific PTEN Knockout Mice
  • 2004-600 Transgenic Mouse with Prostate Specific Expression of a Reporter Gene
  • 2004-073 Murine PTEN Null Prostate Cancer Model
  • 2002-491 Cloned Zebrafish from Long-term Cultured Cells
  • 2002-274 TCL1 Transgenic Mice
  • 2002-135 C-MYC Transgenic Mouse
  • 2002-133 Use of a Gene and Related Mouse Model for the Study and Development of Therapeutics for Neuropsychiatric Disorders
  • 2001-466 Pituitary Adenylyl Cyclase-Activating Peptide (PACAP) Deficient Mice
  • 2001-173 Vasoactive Intestinal Peptide (VIP) and Peptide Histidine Isoleucine (PHI) Knockout Mice
  • 2000-118 Modulation of Neuronal Outgrowth Through Agonism/Antagonism of the Major Histocompatibility Complex Class I (MHC I)
  • 1999-548 A Human Inflammatory Breast Carcinoma Xenograft Model of Theintravasation Step of Metastasis
  • 1998-608 Myeloperoxidase-Deficient Mouse
  • 1996-568 Monoclonal Antibody against Mouse CD1d

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    ANTIBODIES
  • 2012-031 ANTI-HUMAN DEOXYCYTIDINE KINASE (dCK) MONOCLONAL ANTIBODY
  • 2011-418 Novel Monoclonal Antibodies Against Neospora Caninum
  • 2009-592 Anti-S80 Phospho-specific MeCP2 Antibody
  • 2009-306 Polyclonal Antibody Against Histone H3 Lysine 18 Acetylation
  • 2009-010 Monoclonal Antibody Recognizing Human ABL2
  • 2008-745 Novel Monoclonal Phospho-specific Antibody for Btk
  • 2008-735 Antibodies Against Mouse Nuclear Proteins
  • 2008-247 Bi-Specific Monoclonal Antibodies for Rapid Isolation and Expansion of Specific T-Cell Subsets
  • 2007-216 Vectors for Antibody Expression
  • 2006-594 Anti-MAGI-2 Rabbit Polyclonal Antibody
  • 2003-450 Phospho-Specific Antibody for CaM Kinase II
  • 2000-268 End-Specific Antibody To Detect Apoptosis
  • 2000-135 Polyclonal Antibodies Specific to Various Domains of Notch1
  • 1998-610 Hybrid IgA/IgG Polymeric Antibodies
  • 1998-541 Specific Inhibitors of Cytokine Signaling
  • 1997-592 Novel Polyclonal Antibody to Detect a Burton's Tryosine Kinase (Btk) Phosphorylation Site
  • 1997-545 Production of Secretory IgA with Increased Stability

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    BIOMARKERS & SURROGATE MARKERS
  • 2012-421 LABEL-FREE DETECTION OF NUCLEIC ACIDS
  • 2012-180 A Novel Biomarker for Predicting Survival and Response to Treatment in Glioma
  • 2011-872 A Novel Biomarker for Abdominal Aortic Aneurysm (AAA)
  • 2011-746 Genes Dysregulated in Autism as Potential Biomarkers and Therapeutic Targets
  • 2011-774 A Biochemical Fluorometric Method for Assessing the Oxidative Properties of HDL
  • 2010-905METHOD TO ESTIMATE THE AGE OF AN INDIVIDUAL BASED ON EPIGENETIC MARKERS
  • 2010-475 Diagnostic Assays for Detection of B-RAF Inhibitor-Resistant Melanomas
  • 2010-446 Protein Markers for Early Lung Cancer Detection
  • 2009-752 DNA-based Biomarkers for Human Stem Cells and Derivatives
  • 2009-345 RESOLVING INDIVIDUALS CONTRIBUTING TRACE AMOUNTS OF DNA TO HIGHLY COMPLEX MIXTURES USING HIGH-DENSITY SNP GENOTYPING MICROARRAYS
  • 2008-487 Predictive Markers of Response to Dasatinib in Human Colon Cancer
  • 2006-263 Predictive Markers for Dasatinib to Treat Solid Tumors
  • 1994-507 A Sensitive Biomarker of Low-Level Lead Exposure

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    BIOSENSORS & MICROFLUIDICS
  • 2012-612 CONTINUOUS WHOLE-CHIP 3-DIMENSIONAL DEP CELL SORTER AND ITS FABRICATION
  • 2011-143 System and Method for Concentration of P.E.T. Radiotracers
  • 2011-819 NO-ASSEMBLY DEVICES FOR MICROFLUIDICS INSIDE A CAVITY
  • 2011-556 A Digital Microfluidic Chip for Automated Analysis of Protein Structure
  • 2011-207 A CELL PHONE-BASED ELECTRICAL BIOSENSOR
  • 2011-129 Microfluidic and Solid-State Beta Camera In-Vitro Kinase Radioassay
  • 2010-442 METHOD TO IDENTIFY SINGLE NUCLEIC ACID MOLECULES
  • 2010-277 SHEATHLESS INERTIAL CELL ORDERING MICROFLUIDIC DEVICE FOR EXTREME THROUGHPUT FLOW CYTOMETRY
  • 2010-058 LATERAL-FIELD OPTOELECTROWETTING (LOEW) DEVICE FOR OPTICAL DROPLET MANIPULATION ON A SINGLE-PLANAR SURFACE
  • 2009-768 Spontaneous Droplet-into-Droplet Insertion for Formation of Polymer Particles
  • 2009-063 PULSED LASER TRIGGERED HIGH SPEED MICROFLUIDIC SWITCH AND APPLICATIONS IN FLOURESCENT ACTIVATED CELL SORTING
  • 2009-004 PLATFORM FOR SCREENING MEMBRANE PROTEINS AND ION CHANNELS AND FOR DNA SEQUENCING
  • 2009-003 AUTOMATABLE CONTINUOUS FLOW SYSTEM FOR LIPID BILAYER MEMBRANE PRODUCTION
  • 2008-249 Accurate and Rapid Micromixer for Integrated Microfluidic Devices
  • 2008-180 Methods of Fabrication of Robust Microfluidic Systems for Use in Radiochemical Synthesis
  • 2007-570 Integrated Microfluid Platform for Parallel Screening of a Chemical Library
  • 2007-477 Cell Separation Device Using High Electromagnetic Gradients Through a Particle-based Microfluidic Approach
  • 2006-358 Integrated PCR and Electrochemical Biosensor to Detect Biological Samples
  • 2006-077 HYDROGEL-SUPPORTED MEMBRANES
  • 2006-048 SINGLE MOLECULE DNA PROFILING
  • 2005-684 Electrochemically Programmed Assembly of Biological and Chemical Agents
  • 2005-137 Electrochemically Fabricated Conductive Polymer Nanowire Sensors
  • 1994-030 BIO-ELECTRONIC SENSORY DEVICES

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    CELL LINES
  • 2012-524 A Novel Rapid and Highly Sensitive Cell Based System for the Detection and Characterization of HIV
  • 2012-214 METHODS TO PRODUCE CLINICAL-GRADE HUMAN INDUCED PLURIPOTENT STEM CELLS AND DIFFERENTIATED PROGENY
  • 2001-430 CELL-BASED ASSAY TO SCREEN DRUGS TO TREAT HUNTINGTON'S DISEASE
  • 2009-299 Supporting Cell Lines that Improve Gamete Production from Human Pluripotent Cells
  • 2009-187 Selection of E.Coli with Improved Protein Expression
  • 2008-246 Induced Pluripotent Stem Cell Lines and Method to Generate Human Embryonic Stem Cells From Dermal Fibroblasts
  • 2005-059 Pten Null Cell Lines
  • 1999-549 A Feline Bronchioloalveolar Lung Carcinoma (BAC) Xenograft and Cell Line for the Study of Common Animal and Human Pathogens
  • 1999-548 A Human Inflammatory Breast Carcinoma Xenograft Model of Theintravasation Step of Metastasis
  • 1997-545 Production of Secretory IgA with Increased Stability
  • 1991-531 Cell Lines for the Study of Kaposi's Sarcoma and Smooth Muscle Cells

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    CELL & TISSUE CULTURE REAGENTS
  • 2011-475 Novel Approach for Intracellular Delivery of Biomolecules
  • 2011-100 Novel Method to Spatially Program Stem Cell Fate
  • 2011-068 A THERAPEUTIC RELEVANT CULTURE SYSTEM FOR HUMAN NEURAL STEM CELLS AND OLIGODENDROCYTES
  • 2001-067 IN VITRO TISSUE CULTURE ASSAY TO SCREEN POTENTIAL DRUGS FOR HCV
  • 1995-558 ALS CELL CULTURE MODEL

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    CHEMICAL LIBRARIES
  • 2012-293 COMPOUND LIBRARY MADE THROUGH PHOSPHINE-CATALYZED ANNULATION/TEBBE/DIELS-ALDER REACTION

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    DRUG DISCOVERY ASSAYS
  • 2012-474 METHODS, CELLULAR COMPOSITIONS, AND AGENTS THAT REGULATE AN IMMUNE RESPONSE TO CANCER
  • 2012-471 METHODS AND SYSTEMS FOR MODULATING HORMONES AND RELATED METHODS, AGENTS AND COMPOSITIONS
  • 2012-271 AN APPROACH TO DERIVE MOLECULAR SIGNATURES OF AGGRESSIVE LUNG CANCER
  • 2011-398 A System for Vascular Access in Preclinical Models
  • 2011-351 Novel Selective Inhibitors of Pro-Inflammatory Gene Expression for the Treatment of Inflammatory Conditions and Associated Screening Techniques
  • 2011-211 Protein Hydrogel Based Paper Assay (PGPA)
  • 2010-304 A HIGH THROUGHPUT ASSAY FOR IDENTIFYING PTC READTHROUGH COMPOUNDS AND RESULTING COMPOUNDS
  • 2009-588 A Rapid Assay to Assess Raltegravir Levels in Biological Samples
  • 2009-381 IDENTIFICATION OF SMALL MOLECULES THAT FACILITATE THERAPEUTIC EXON SKIPPING
  • 2009-076 HIGH THROUGHPUT SCREEN FOR NOVEL TYROSINE KINASE INHIBITORS
  • 2009-004 PLATFORM FOR SCREENING MEMBRANE PROTEINS AND ION CHANNELS AND FOR DNA SEQUENCING
  • 2009-003 AUTOMATABLE CONTINUOUS FLOW SYSTEM FOR LIPID BILAYER MEMBRANE PRODUCTION
  • 2003-448 MONITORING MOLECULAR INTERACTIONS USING PHOTON ARRIVAL-TIME INTERVAL DISTRIBUTION (PAID) ANALYSIS
  • 2001-430 CELL-BASED ASSAY TO SCREEN DRUGS TO TREAT HUNTINGTON'S DISEASE
  • 1992-253 ASSAY FOR HUMORAL IMMUNITY TO MACROMOLECULES

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    DRUG TARGETS
  • 2012-420 CCYLINDRIN: THE POSSIBLE GENERIC ETIOLOGIC AGENT OF AMYLOID DISEASE
  • 2012-395 A NON-SURGICAL TREATMENT OF HUMAN CATARACTS
  • 2011-746 Genes Dysregulated in Autism as Potential Biomarkers and Therapeutic Targets
  • 2010-593 IDENTIFICATION OF A NEW RETINOID ISOMERASE IN RETINAS THAT REGENERATES VISUAL CHROMOPHORE
  • 2010-475 Diagnostic Assays for Detection of B-RAF Inhibitor-Resistant Melanomas
  • 2009-302 Translation Factors as Anti-Aging Drug Targets
  • 2008-245 AN ANTIGEN-SPECIFIC RECEPTOR TO RECOGNIZE MELANOMA CANCER CELLS
  • 2004-275 A MXXXL Motif Confering Endocytosis of Biomolecules
  • 2004-096 Identification of the First Human Glucose Sensor—A New Target for Treatment of Diabetes, Obesity, and Related Metabolic Disorders
  • 2000-479 GDOX, A Novel Candidate Proto-oncogene
  • 2000-236 Granulin as a Target for Tumor Diagnosis and Growth Regulation

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    GENE & PROTEIN EXPRESSION SYSTEMS
  • 2010-478 REAL TIME GENE EXPRESSION ANALYSIS IN LIVE CELLS
  • 2009-571 Novel Inhibitors of HIV-1 Integrase
  • 2009-527 INCORPORATION OF NON-NATURAL AMINO ACIDS INTO PROTEINS AND ITS APPLICATION TO PRODUCTION OF PHARMACEUTICAL INTERMEDIATES
  • 2009-297 Light-Regulated Gene Expression Systems in Yeast and Human Cells
  • 2008-374 pH-Responsive Nanovalves
  • 2005-314 PROTEIN-PROTEIN INTERACTIONS AS A TOOL FOR SITE-SPECIFIC LABELING OF PROTEINS
  • 2004-596 THE USE OF SKELETAL MUSCLE FOR LARGE-SCALE PRODUCTION AND EXPORT OF RECOMBINANT TRANSMEMBRANE PROTEINS

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    IMAGING AGENTS
  • 2011-395 New Low-Cost Method for Pre-clinical Animal Imaging
  • 2011-394 A Statistical Atlas of the Mouse Trunk Region
  • 2010-669 Visualization of Alzheimer's Disease on MRI
  • 2010-257 BIOLUMINESCENCE REPORTER HIV FOR NON-INVASIVE IMAGING
  • 2006-704 Two-color Fluorescent Reporter For Alternative Pre-MRNA Splicing
  • 2004-095 SYNTHESIS OF NEAR-IR EMITTING CORE/SHELL NANOCRYSTALS FOR IN VIVO BIOLOGICAL APPLICATIONS
  • 2001-202 A Novel Fluorescent-based Screen to Identify Small Synthetic Internal Ribosome Entry Site (IRES) Elements
  • 1997-543 Reaction of Purines with Elemental Fluorine to Generate 8-Fluoropurines
  • 1995-543 RNA Binding Fluorochrome: Fluoro Nissl Green

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    PLASMIDS & VECTORS
  • 2012-524 A Novel Rapid and Highly Sensitive Cell Based System for the Detection and Characterization of HIV
  • 2007-216 Vectors for Antibody Expression
  • 1993-554 A SMALL RNA WHICH SELECTIVELY INHIBITS PICORNAVIRAL RNA TRANSLATION
  • 1993-201 HTLV-IINRA COMPOSITIONS AND ASSAYS FOR DETECTING HTLV INFECTION

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    SOFTWARE TOOLS
  • 2012-475 INDOOR GPS NAVIGATION ASSISTANCE FOR THE PHYSICALLY DISABLED
  • 2011-395 New Low-Cost Method for Pre-clinical Animal Imaging
  • 2011-394 A Statistical Atlas of the Mouse Trunk Region
  • 2006-296 KNOWLEDGE MANAGEMENT SOFTWARE

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    ADDITIONAL TOOLS
  • 2012-613 SERUM FREE MEDIUM FOR NEURONAL SPECIFICATION AND FUNCTIONAL MATURATION
  • 2009-412 High-purity Separation of Target Species using Microfluidics Conduits
  • 2009-309 Ready-to-Use Detection of Melamine
  • 2009-297 Light-Regulated Gene Expression Systems in Yeast and Human Cells
  • 2009-085 Cross Coupling of Phenolic Derivatives
  • 2009-047 Peptide Epitopes as Biomarkers for Prostate Cancer
  • 2009-004 Droplet Membrane Formation with Integrated Electrode
  • 2008-663 Optimized Matrix Based Virus-like Particle Entry and Budding Assay for Highly Pathogenic Viruses
  • 2008-374 pH-Responsive Nanovalves
  • 2008-249 Accurate and Rapid Micromixer for Integrated Microfluidic Devices
  • 2007-570 Integrated Microfluid Platform for Parallel Screening of a Chemical Library
  • 2007-564 Minimally Invasive Single-cell Surgery Tool Based on Photothermal Effects of Metal Nanoparticles
  • 2007-477 Cell Separation Device Using High Electromagnetic Gradients Through a Particle-based Microfluidic Approach
  • 2007-192 A Novel Nanoparticle-based Catalyst for Organic Reactions in a General Aqueous
  • 2006-625 Proton-sensing G Protein-couipled Receptor 4 Knockout
  • 2006-558 2006-558 Converting Genomic Protein Sequences into Music
  • 2006-276 ASSESSING THE TOXIC POTENTIAL OF MATERIALS AT THE NANOLEVEL
  • 2005-246 Intelligent Response-Dependent Stimulation of Cells for Basic Research and Drug Discovery Applications
  • 2005-242 Non-Invasive Assessment of Intracranial Pressure
  • 2005-129 pVEGF-TSTA-Luciferase Mice
  • 2004-487 A Method of Introducing an Artificial Allosteric Site on a Funtional Protein and Use of an External Modulator to Affect its Substrate Binding and Catalysis Rate for Diagnostic and Research Applications
  • 2004-395 Novel Micro-Calorimeter Device for Drug Discovery and Biochemical Analysis
  • 2003-053 Genetically Engineered Mouse Lacking Tumor Suppressor Gene in the Brain
  • 1999-262 IDENTIFICATION OF SORTASE
  • 1994-534 Selective Localization of Ultrasound Contrast Agent

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