http://www.oip.ucla.edu/therapeutics
THERAPEUTICS AND PHARMACEUTICALS
AUTOIMMUNE
2012-140 A NOVEL APPROACH FOR ALLERGY THERAPEUTIC 2011-776 Small Molecule Suppressors of Immune Function
2008-799 Genomic Predictor of Kidney Cancer Prognosis and IL-2 Treatment Response
2008-560 Reversing the Loss of Immune Function in Aged Populations Through the Induction of Antioxidant Activity by a Gene Regulatory Pathway
2008-369
Fungal Immunosuppressive Compounds 2008-211 Peptide for Induction of Immune Tolerance as Treatment for Systemic Lupus Erythematosus (SLE)
2001-425 Receptor Interacting Protein 2 (RIP2) in Development of Immune Response
1998-541 Specific Inhibitors of Cytokine Signaling
1997-505 A Protein of Mycobacterium Tuberculosis Stimulates Interleukin-12 Production
1991-543 Natural Killer Enhancing Factor
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CARDIOVASCULAR
2012-694
TREATING ATRIAL FIBRILATION BY TARGETING SUPEROXIDE PRODUCTION 2011-417 A Small Molecule Inhibitor of Cholesterol Biosynthesis and Angiogenesis 2010-769
Growth Factor Treatment of Myocardial Infarction
2008-235 Genetic Engineering of Skeletal Muscle Cells for Autologous Cell Transplantations
2006-397 HUMAN KUNITZ-TYPE INHIBITOR 2001-429 5-Lipoxygenase, A New Therapeutic and Diagnostic Target for Heart Disease Management
1996-592 Cerberus and FRZB-1, Secretory Molecules with a Regenerative Function and an Inhibitory Activity on WNTS, Respectively
1996-528 Method and Device for Treating Intracranial Vascular Aneurysms
1993-501 Organic Compounds for the Treatment of Myocardial Infarction
1991-543 Natural Killer Enhancing Factor
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DERMATOLOGY
2012-558
Diagnosis and Personalized Acne Therapy
2006-264 Nano Particles with Natural Anti-microbial Properties
2005-351 Broad-spectrum Anti-microbial Peptide for the Treatment of Acne and Skin Cancer
2001-194 Wit 3.0, a Novel Gene to Control Soft Tissue Wound Healing
1997-505 A Protein of Mycobacterium Tuberculosis Stimulates Interleukin-12 Production
1996-592 Cerberus and FRZB-1, Secretory Molecules with a Regenerative Function and an Inhibitory Activity on WNTS, Respectively
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ENDOCRINE
2012-065 Small Molecules for Islet Expansion in the Treatment of Diabetes
2002-428 Polyphenolic Compounds Inhibit Pancreatic Cancer
2002-427 Curcumin as a Treatment for Pancreatitis
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GI
2012-704
Peptide Treatment for Microbial Intestinal Inflammation 2012-604 NANOPARTICLES FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE 2012-129 NOVEL PROTOCOLS FOR ERADICATION OF H. PYLORI 2011-293 A Novel Small Molecule Therapy to Prevent and Treat GI Inflammatory Diseases, Including GERD and Ulcers | BACK TO SEARCH-TECHS TOP OF PAGE CONTACT
HEMATOLOGY
2012-730 LENTIVIRAL VECTOR FOR STEM CELL GENE THERAPY OF SICKLE CELL DISEASE | BACK TO SEARCH-TECHS TOP OF PAGE CONTACT
INFECTIOUS DISEASES
2012-704
Peptide Treatment for Microbial Intestinal Inflammation 2012-623 COMBINATION SHRNA VECTOR FOR HIV DISEASE 2012-556 NOVEL METHODS FOR THE TREATMENT AND PREVENTION OF PERSISTANT VIRAL INFECTION 2012-332 BIMODAL VACCINATION STRATEGY AGAINST TUBERCULOSIS 2012-260 CHEMICAL COMPOUNDS THAT INHIBIT THE REPLICATION OF ENTEROVIRUSES AND OTHER PICORNAVIRUSES 2012-259 A SMALL MOLECULE INHIBITOR OF MICROBIAL VIRULENCE FACTORS 2012-029 Inhibition of Hepatitis C Virus Ns5a
2011-562 Method for Manufacturing Potent Dendritic Cells
2010-657 Novel Live Recombinant Booster Vaccine Against Tuberculosis
2011-531 SMALL MOLECULES THAT MIMIC INTERFERON-GAMMA-MEDIATED ENDOTHELIAL CELL ACTIVATION
2010-395 Molecules in Hops for the Treatment of Human Pathogenic Bacteria
2010-079
Azuvirins: Novel Peptides with Potent Anti-cancer and Anti-viral Properties
2009-666 Novel Small Molecules to Treat MRSA and Other Bacterial Infections
2009-655
Safe and Potent Vaccines Against Tularemia 2009-252 Anti-viral T-Cell Therapy from Stem Cells
2009-055 HAPIVIRINS AND DIPROVIRINS NOVEL PEPTIDES ACTIVE AGAINST HIV1 2009-002 ANTIMICROBIAL MESOPOROUS SILICA NANOPARTICLES 2007-223 Novel Vaccines Against Tularemia
2006-539 New Recombinant Tuberculosis BCG Vaccine for Immunocompromised Patients and Others
2006-538 Recombinant Tuberculosis BCG Vaccine Elicits a Highly Protective Host Immune Response
2006-264 Nano Particles with Natural Anti-microbial Properties
2005-765 CYCLIC PEPTIDES HAVING BROAD SPECTRUM ANTIMICROBIAL ACTIVITY 2004-046 Improved TB Vaccine Strategy Utilizing a Booster Protein for People Vaccinated with BCG
2002-483 Novel Signaling Molecule Utilized By S. Mutans for Bio-film Formation and Quorum Sensing
2002-427 Curcumin as a Treatment for Pancreatitis
2001-329 Retrocyclin: an Anti-Retroviral Circular Minidefensin
2000-313 NOVISPIRINS: ANTIMICROBIAL PEPTIDES ACTIVE AGAINST PSEUDOMONAS 1999-556 HIV Protein Moderates Telomerase
1998-560 LEPTOSPIRAL SURFACE-EXPOSED LIPOPROTEIN 1997-505 A Protein of Mycobacterium Tuberculosis Stimulates Interleukin-12 Production
1996-604 Targeted Prophylactic and Chemotherapeutic Agents Againstmycobacterium Tuberculosis
1996-546 OUTER MEMBRANE ASSOCIATED PROTEINS OF LEPTOSPIRA SP 1995-600 NOVEL PROTEGRIN-RELATED ANTIMICROBIAL PEPTIDES 1995-579 Anti-Microbial Targeting for Intracellular Pathogens
1995-565 LIPL2, A MEMBRANE LIPOPROTEIN OF LEPTOSPIRA KIRSCHNERI 1994-518 Prophenins: Proline-Rich Antimicrobial Peptides with Repetitive Decamersequence
1993-564 Novel Gene Therapy for AIDS Using Mutated tRNAs
1993-540 PROTEGRINS: NOVEL MAMMALIAN ANTIBIOTIC PEPTIDES 1992-529 A CLONED ANTIGEN FOR IMPROVED DETECTION AND PREVENTION OF LEPTOSPIROSIS 1992-510 Immunoglobulin Superantigen Binding to GP120 from HIV
1991-561 Restoration of Impaired Cellular Immune Function
1991-543 Natural Killer Enhancing Factor
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INFLAMMATORY
2012-704
Peptide Treatment for Microbial Intestinal Inflammation 2012-640 RECEPTOR INTERACTING PROTEIN 2 IN MODULATING INNATE AND ADAPTIVE IMMUNITY 2012-140 A NOVEL APPROACH FOR ALLERGY THERAPEUTIC 2011-875 Inhibition of a Macrophage-Specific Pathway to Treat Malignant Ascites
2011-776 Small Molecule Suppressors of Immune Function
2011-531 SMALL MOLECULES THAT MIMIC INTERFERON-GAMMA-MEDIATED ENDOTHELIAL CELL ACTIVATION
2011-351
Novel Selective Inhibitors of Pro-Inflammatory Gene Expression for the Treatment of Inflammatory Conditions and Associated Screening Techniques 2002-427 Curcumin as a Treatment for Pancreatitis
1995-573
Use of Taxol in the Treatment of Rheumatoid Arthritis | BACK TO SEARCH-TECHS TOP OF PAGE CONTACT
METABOLIC
2012-065 Small Molecules for Islet Expansion in the Treatment of Diabetes
2011-743 Regulation of Adipocyte Differentiation to Control Obesity
2010-443 Small Molecule Treatment for Type 2 Diabetes 2010-391 MITOCHONDRIA TREATMENT 2010-008 SMALL MOLECULE MODULATORS OF ALKALINE PHOSPHATASE FUNCTION 2009-720
Novel use of GABA to Treat Metabolic Syndrome, Type 2 Diabetes, and Other Related Diseases
2008-210 Hypocretin (HCRT-1) Administration to Treat Narcolepsy and Obesity
2005-604 Soluble and Cell-Associated Hemojuvelins as a Therapy and Diagnostic for Iron Metabolism Diseases
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MUSCULOSKELETAL
2011-061 Conversion of Normal Human Keratinocytes to Pluripotent Stem Cells for Treatment of Bone Loss
2010-095 NOVEL OSTEOGENIC COMPOUNDS 2008-483 Parathyroid Hormone (PTH) Supplement for Osteoporosis
2007-145 Small Protein-mediated Therapy for the Treatment of Muscular Dystrophy
1999-560 NELL-1 Protein with Activity in Bone Formation
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NEUROLOGY
2012-615 NEW COMPOUNDS FOR THE TREATMENT OF DISEASES RELATED TO PROTEIN MISFOLDING 2012-180 A Novel Biomarker for Predicting Survival and Response to Treatment in Glioma
2012-172 Nerve Agent Antidote Kit
2011-742 Macrocyclic Inhibitors for Drug Design
2011-741 Identification of Therapeutics for Parkinson's Disease and Other Neuropsychiatric Disorders using a Novel Functional Screen
2011-329 New Use of Drug for Psychosis and Bipolar Disorder 2011-294 Aminoacylase 3 (AA3) Inhibitors for the Prevention and Treatment of Alzheimer's and Parkinson's Disease 2011-292
Pharmacophores for Amyloid Fibers Involved in Alzheimer’s Disease 2011-101 Use of a Purified Flavonoid Compound to Prevent Fetal Alcohol Exposure-Induced Behavioral Disorders Including Adolescent Alcohol Abuse
2011-063 Receptor Pathway and Potential Drug Target for Astrocyte Related Disorders of the Nervous System
2010-472 Use of a Purified Flavonoid Compound to Prevent Alcohol Tolerance and Dependence
2010-174 ANTIBODY-MEDICATED TRANSDUCTION OF HSP70 INTO LIVING CELLS 2009-717 USE OF PYROGLUTAMYL-GLUTAMYL-PROLYL AMIDE (EEP) FOR NEUROLOGICAL AND NEUROBEHAVIORAL DISORDERS 2009-626 VITAMIN D AND ALZHEIMER DISEASE 2009-384 Novel Compounds for the Treatment of Essential Tremor
2009-269
A Semi-synthetic Approach to the Production of Keppra 2009-187 SELECTION OF E COLI WITH IMPROVED PROTEIN EXPRESSION 2008-489
Small Molecule “Molecular Tweezers” that Inhibit
Amyloid-β Fiber Formation 2008-210 Hypocretin (HCRT-1) Administration to Treat Narcolepsy and Obesity
2007-791 Estrogen Receptor Ligand Treatment for Neurodegenerative Diseases
2004-598 Breakthrough Treatment for the Learning and Memory Deficiencies Associated with Neurofibromatosis Type 1
2002-133 Use of a Gene and Related Mouse Model for the Study and Development of Therapeutics for Neuropsychiatric Disorders
2000-236 Granulin as a Target for Tumor Diagnosis and Growth Regulation
2000-128 Targeting Lentiviral Vectors to Specific Cells and Tissues
2000-118 Modulation of Neuronal Outgrowth Through Agonism/Antagonism of the Major Histocompatibility Complex Class I (MHC I)
1996-615 Mutations in Ataxia-Telangiectasia Gene
1996-592 Cerberus and FRZB-1, Secretory Molecules with a Regenerative Function and an Inhibitory Activity on WNTS, Respectively
1996-588 BROMOCRIPTINE IN THE TREATMENT OF ALCOHOLICS WITH THE A1 ALLELE OF DRD2 1996-580 ALTERED REACTIVITY OF SUPEROXIDE DISMUTASE IN FAMILIAL AMYOTROPHIC LATERAL SCLEROSIS 1991-573 Cloned Vesicular Amine Transporters and Methods for Drug Screeningand Gene Therapy
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ONCOLOGY
2012-733
Novel Therapeutic Analogues of Metformin for the Treatment of Cancers 2012-602 COMBINATION DRUG THERAPY FOR THE ACTIVATION OF EPIGENETICALLY SILENCED GENES 2012-601
Novel Small Molecules that Target Cancer Stem Cells for the Treatment of Cancer 2012-395 A NON-SURGICAL TREATMENT OF HUMAN CATARACTS 2012-359 Drug Therapy for Prostate Cancer 2012-220 TREATMENT OF BREAST CANCER WITH COMPANION DIAGNOSTIC 2012-215 Small Molecule Read-through Compounds for Treating Genetic Diseases
2011-875 Inhibition of a Macrophage-Specific Pathway to Treat Malignant Ascites
2011-562 Method for Manufacturing Potent Dendritic Cells
2011-531 SMALL MOLECULES THAT MIMIC INTERFERON-GAMMA-MEDIATED ENDOTHELIAL CELL ACTIVATION
2011-417 A Small Molecule Inhibitor of Cholesterol Biosynthesis and Angiogenesis 2011-017 NANOPARTICLE BASED siRNA/DRUG DELIVERY SYSTEM 2011-011 A NEW TYPE OF NANODRUG FOR CANCER THERAPY
2010-594 Antibody Fusion Proteins with Disrupted Heparin Binding Activity
2010-272 Spp24: A Small Protein that Inhibits Tumor Growth in an Animal Model of Bone Metastasis
2010-079 AZUVIRINS: NOVEL PEPTIDES WITH ANTIVIRAL AND ANTINEOPLASTIC POTENTIAL 2009-677 NOVEL OXYSTEROLS THAT INHIBIT HEDGEHOG SIGNALING
2009-591 INHIBITION OF TUMOR METASTASIS BY PROTEASOME INHIBITORS
2008-738 Diagnostic and Therapeutic Utility of Cystatin E/M for Cervical Cancer
2008-375
Enzyme-Driven Nanovalves for On-Demand Release of Guest Molecules
2008-374
pH-Responsive Nanovalves
2007-406 Protection Against Radiation
2007-347
Use of Natural Killer (NK) Cells in Cancer Treatment 2007-310 Improved Drug Delivery to Cancer Cells Using Modified Transferrin
2006-357 Novel Non-peptidomimetic Prenyl Transferase Inhibitors
2004-073 Murine PTEN Null Prostate Cancer Model
2002-428 Polyphenolic Compounds Inhibit Pancreatic Cancer
2002-422 A Method to Induce Anti-Viral Responses
2001-381 Use of Secondary Lymphoid Organ Chemokine to Induce Anti-tumor Response by Stimulating Cell-mediated Immune Response and Inhibiting Angiogenesis
2000-479 GDOX, A Novel Candidate Proto-oncogene
2000-236 Granulin as a Target for Tumor Diagnosis and Growth Regulation
1999-556 HIV Protein Moderates Telomerase
1999-402 Diagnostic and Therapeutic Methods Using the H37 Tumor Suppressor Gene
1998-556 GM-CSF and IL-4 Therapy for the In-Situ Expansion of Dendritic Cells and Enhancement of Vaccine-based Immunity
1998-541 Specific Inhibitors of Cytokine Signaling
1997-505 A Protein of Mycobacterium Tuberculosis Stimulates Interleukin-12 Production
1996-615 Mutations in Ataxia-Telangiectasia Gene
1996-569 TUMOR RADIOSENSITIZATION BY GENE THERAPY 1993-581 MECHANISM OF INHIBITION OF CELL DEATH BY BCL-2 1991-515 Method and Composition for Treatment of Kaposi's Sarcoma
1990-544 REVERSIBLE ENHANCEMENT OF CELLULAR GROWTH | BACK TO SEARCH-TECHS TOP OF PAGE CONTACT
OPHTHALMOLOGY
2012-395 Non-Surgical Treatment of Cataracts
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RESPIRATORY
2007-105 Small Molecule Therapeutic for Treating Asthma and Other HIF1 Associated Conditions
2000-377 Live Recombinant Tuberculosis Vaccine
1999-402 Diagnostic and Therapeutic Methods Using the H37 Tumor Suppressor Gene
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UROLOGICAL
2004-084 Stemcell Urinary Tract Reconstruction therapy
1996-525 Treatment of Polycystic Kidney Disease: Pharmacological Compounds and In-Vitro Screening System
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OTHER
2012-521 A PRENYLATED ANTHRACENONE POLYKETIDES AS AN IMMUNOSUPPRESSANT 2012-516 SMALL MOLECULES TO COUNTER AGING AND AGE-RELATED DISEASES 2012-340 A Novel Basic Fibroblast Growth Factor Conjugate for Broad Therapeutic Application 2012-411
Device for the Treatment and Prevention of Radiation Induced Proctitis
2012-292 ORGAN RESUSCITATION SOLUTION AND SYSTEM FOR ENHANCED LIVER TRANSPLANTATION 2010-504 INHIBITION OF HAIR GROWTH 2010-391 MITOCHONDRIA TREATMENT 2010-043 METHODS FOR DYNAMIC MODIFICATION OF LOCALIZED CELLULAR ENVIRONMENTS 2009-381 IDENTIFICATION OF SMALL MOLECULES THAT FACILITATE THERAPEUTIC EXON SKIPPING 2008-693 New Use of a Pharmaceutical to treat Snoring, Sleep Apnea and Related Disorders
2008-210 Hypocretin (HCRT-1) Administration to Treat Narcolepsy and Obesity
2006-584 Drug for Dialysis-related Amyloidosis
2004-675 An Intelligent Nanomedicine Integrating Diagnosis and Therapy
2004-522 Compounds for Treating Microbial Infections in the Oral Cavity, for Incorporating into Consumer Oral Health Products
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