Dr. Ronald Busuttil
Director, Dumont-UCLA Liver Transplant Center

 

Within the next 50 years, liver transplantation will have a much different look. While today we primarily rely on cadaveric donation, tomorrow's organs may be laboratory-grown as a result of the advances that will be made in genomics, stem cell research and cloning. With these new techniques, living-related liver transplantation, which puts the donor at risk, will no longer be used. The rejection process will be better understood, and anti-rejection drugs will be improved to the point where they induce a permanent state of tolerance for transplanted organs. Animal organs -- xenografts -- will probably not be used. Although these new advances will simplify and improve the results of transplantation, mainly by decreasing the side effects, newer discoveries in the prevention and treatment of diseases such as hepatitis and cirrhosis will likely preclude the need for transplantation in these patients 50 years hence.

 

Copyright 2002 Regents of the University of California
Article originally appeared in:
UCLA Medicine, Volume 22, Number 1
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