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Allelic Diagnosis of Susceptibility to Compulsive Disorders
Participating UCLA Inventor:
Ernest P. Noble
A method for diagnosing and detecting compulsive disorder susceptibility of an individual. The method
consists of initially obtaining a DNA sample of the individual and then determining the presence or absence of particular human D2 receptor gene alleles in the sample.
U.S. Patent No. 5,550,02
Issued: August 27, 1996
Immobilized Free Molecule Aerosol Catalytic Reactor
Participating UCLA Inventor:
Sheldon K. Friedlander
A catalytic reactor bed in which support particles in the free molecule size range from 50 to 500 angstroms are attached to an anchor surface to form a dendritic network extending from 10 microns to 300 microns
outward from the anchor surface.
U.S. Patent No. 5,541,147
Issued: July 30, 1996
DNA's Encoding Natural Killer Cell Enhancing Factor
Participating UCLA Inventors:
Hungyi Shau, Sidney H. Golub
Recombinant DNA molecules comprising a DNA sequence encoding either NKEF (Natural Killer Enhancing Factor)-A or -B or their amino acid sequence variants. Methods for protection of cells and cellular components from oxidant damage by NKEF-A or -B, now renamed thioredoxin peroxidase-A, -B (TxP-A, -B). TxP-A blocks c-Abl mediated cell cycle arrest and signal transduction.
TxP-B protects cells from genotoxins, including cancer drugs.
U.S. Patent No. 5,610,286
Issued: March 11, 1997
Method for Mammalian Cell Transfection
Participating UCLA Inventors:
Peter Edwards, David H. Spear
The invention relates to a process for transfecting a mammalian cell culture. The process includes incubating a cell culture in the presence of a transfection medium that includes a serum that is of a different type from the serum used in the normal growth medium used to grow the cell culture.
U.S. Patent No. 5,589,368
Issued: December 31, 1996
Monolithic Passive Component
Participating UCLA Inventors:
Asad A. Abidi, James Y. C. Chang
An integrated circuit having a
monolithic device such as an inductor
suspended over a pit in the substrate to reduce parasitic capacities and enhance the self-resonant
frequency of the inductor.
U.S. Patent No. 5,539,241
Issued: July 23, 1996
Hematopoietic Restricted
Tyrosine Kinase (BPK)
Participating UCLA Inventors:
Owen N. Witte, David Rawlings, Satoshi Tsukada, Douglas Saffran
Novel hematopoietic-restricted tyrosine kinases are provided, where the tyrosine kinases provide for autophosphorylation and transphophorylation. Modulation of the activity of the subject compositions can be used to restrict growth and differentiation, to correct genetic deficiencies, and to elucidate the activation pathway involved with the subject tyrosine kinases.
U.S. Patent No. 5,550,054
Issued: August 27, 1996
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IgE Isoforms and Methods of Use
Participating UCLA Inventors:
Andrew Saxon, Ke Zhang
Methods and compositions are provided relating to novel IgE isoforms and their use in immune hypersensitivity diagnosis and treatment. The compositions include transcription and translation products of the immunoglobulin epsilon locus, specific probes for epsilon transcription products, and compounds, which specifically bind epitopes of epsilon translation products.
U.S. Patent No. 5,552,537
Issued: September 3, 1996
Highly Efficient, Ultrafast Optical-to-Electrical Converter and Method of Operating the Same
Participating UCLA Inventors:
Tatsuo Itoh, Ming-Chiang Wu
The periodic array of photodiodes are disposed in a passive optical waveguide electrically coupled in series with each other by microwave transmission line. The collective array of photodiodes coupled to the optical waveguide and microwave transmission line results in an increased bandwidth-efficiency product for the photodetector array as compared to any single photodetector within the array.
U.S. Patent No. 5,572,014
Issued: November 5, 1996
Cloned Borrelia Burgdorferi Virulence Protein
Participating UCLA Inventors:
David Blanco, Cheryl Champion,
Michael A. Lovett, James N. Miller,
David A. Haake
The invention is based on the identification of the novel protein which is a Borrelia burgdorferi exported protein associated with virulence of Borrelia. The invention describes a 17 kD outer membrane protein from Borrelia burgdorferi and the gene encoding the protein.
U.S. Patent No. 5,558,993
Issued: September 24, 1996
Quantum Bridges Fabricated
by Selective Etching Superlattice Structures
Participating UCLA Inventors:
Martin Tanner, Kang L. Wang
A quantum bridge structure including wires of a semiconductor material such as silicon which are formed by selectively etching a superlattice of alternating layers of at least two semiconductor materials. A quantum bridge structure may be useful as a photo emission device, a photo detector device, or a chemical sensor.
U.S. Patent No. 5,539,214
Issued: July 23, 1996
Method for Increasing the Resistance of Neural Cells to B-Amyloid Peptide Toxicity
Participating UCLA Inventor:
Dale E. Bredesen
Neural cells which express P75 nerve growth factor receptor (p75NTR) and which have a low resistance to b-Amyloid peptide toxicity are treated with a binding agent that binds with p75NTR. The resulting neural cells display an increased resistance to b-Amyloid toxicity.
U.S. Patent No. 5,576,209
Issued: November 19, 1996
Gallinacins Antibiotic Peptides
Participating UCLA Inventors:
Robert I. Lehrer, Vladimir N. Kokryakov, Sylvia S.L. Harwig
Peptide-based compounds containing six invariant cysteine residues are useful as preservatives and in preventing, treating or ameliorating microbial infection in animals and plants.
U.S. Patent No. 5,635,594
Issued: June 3, 1997
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