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Use of Pharmaceutical-Grade Compounds
In accordance with the NIH Office of Laboratory Animal Welfare and USDA Animal Care Policy # 3 , the Animal Research Committee (ARC) has established the following guidelines:
  • Investigators are expected to use pharmaceutical-grade medications whenever they are available, even in acute procedures.
  • Non-pharmaceutical-grade chemical compounds should only be used in animals after specific review and approval by the ARC for reasons such as scientific necessity or non-availability of an acceptable veterinary or human pharmaceutical-grade product. Cost savings is not an adequate justification for using non-pharmaceutical-grade compounds in animals.
  • All non-pharmaceutical-grade compounds must be filter-sterilized using a 0.22 µm filter prior to administration.

Approved 11/13/00

Revised 6/02, 7/28/03, 8/10/09